C5b-9 (aE11) Antibody sc-58935 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemC5b-9 (aE11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Numbersc-58935
NCBI Gene AliasesECLZB, CPAMD4, ARMD15, C5D, C5b, C5a, C9D
Antibody TypePrimary Antibodies
CloneaE11
Quantity100 µg/ml
ApplicationsIF, ELISA
Reactivityhuman, porcine
FormatPurified
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Full Gene Namecomplement C5, complement C6, complement C8 alpha chain, complement C9, complement C7
TargetC5b-9
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Anti-C5 Antibody Tesidolumab Reduces Early Antibody Mediated Rejection and Prolongs Survival in Renal Xenotransplantation.Annals of SurgerySeptember 1, 2021Andrew B. Adams, Brendan P. Lovasik, David A. Faber, Christopher Burlak, Cynthia Breeden, Jose L. Estrada, Luz M. Reyes, Rodrigo M. Vianna, Matthew F. Tector, Alfred J. Tectorantibodies: anti-C4d (Lifespan Bioscience # LS-C140137–100) and anti-C5b-9 (Santa Cruz Biotechnology #SC-58935); secondary antibody: anti-human IgG # 309–486-003, anti-human IgM #309–606-043 both conjugated to alexafluor

(2) Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killingClinical & Translational ImmunologyApril 3, 2021Jeroen D Langereis et al.both AP and CP analyses. Plates were washed 2× with wash buffer. Mouse aE11 monoclonal anti‐C5b‐9 (sc‐58935; Santa‐Cruz Biotechnologies, Santa Cruz, CA, USA) was diluted 1000‐fold in wash buffer, added to the

(3) The Clinicopathological Distinction Between Seropositive and Seronegative Immune-Mediated Necrotizing Myopathy in ChinaFrontiers in neurologyJanuary 1, 2021Ma X, Xu L, Ji S, Li Y, Bu B.(MHC-I) (1:100, ab23755, Abcam) on the sarcolemma, deposition of membrane attack complex (MAC) (1:50, Sc-58935, Santa Cruz Biotechnology) on the sarcolemma and vasculature, and presentation of p62 (sequestosome

(4) Ex vivo assays to detect complement activation in complementopathiesClinical ImmunologyDecember 1, 2020Xuan Yuan, Jia Yu, Gloria Gerber, Shruti Chaturvedi, Michael Cole, Hang Chen, Ara Metjian, C. John Sperati, Evan M. Braunstein, Robert A. Brodskyroom temperature (RT), washed once with PBS, and stained with C5b-9 monoclonal primary antibody (Cat. sc-58935, Santa Cruz Biotechnology, Inc., 1:50 dilution). The plate was incubated for 30 min on ice. After incubation,

(5) Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal DegenerationCell reportsFebruary 18, 2020Mulfaul K, Ozaki E, Fernando N, Brennan K, Chirco KR, Connolly E, Greene C, Maminishkis A, Salomon RG, Linetsky M, et al.IHC,Biozol,Cat# FGI-10–1801 MAC/ anti-C5b-9 for human IHC,Santa Cruz Biotechnology,clone aE11; Cat# sc58935; RRID: AB_1119839 MAC/ anti-C5b-9 for WB,Santa Cruz Biotechnology,Clone 2A1; Cat# sc66190; RRID: AB_1119840 Anti-CEP,"Dr.

(6) Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPSBloodJanuary 23, 2020Shruti Chaturvedi et al.rpm for 3 min at room temperature and then stained with anti-C5b-9 monoclonal primary antibody (1:50; sc-58935; Santa Cruz Biotechnology) for 30 min, followed by Alexa 647-conjugated secondary antibody (1:500; Ab172325;

(7) Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplificationNature CommunicationsDecember 1, 2018Anuj Pathak, Jan Bergstrand, Vicky Sender, Laura Spelmink, Marie-Stephanie Aschtgen, Sandra Muschiol, Jerker Widengren, Birgitta Henriques-Normark20% NHS (Sigma) followed by incubation with anti-C5b-9 antibody (αE11), (Santa cruz biotechnology, sc-58935, 1:50). Alexa fluor 488 labeled secondary antibody (Life Technologies, A11001, 1:100) was used for further

(8) 4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial CellsChemical research in toxicologyAugust 20, 2018Linetsky M, Bondelid KS, Losovskiy S, Gabyak V, Rullo MJ, Stiadle TI, Munjapara V, Saxena P, Ma D, Cheng YS, et al.Mouse monoclonal anti-human C5 antibody (sc-52636) and mouse monoclonal anti-human C5b-9 antibody (SC-58935) and HRP-conjugated laminin B1 (nuclear proteins loading control, sc-374015 HRP) were obtained from

(9) Complement System as a Target for Therapies to Control Liver Regeneration/Damage in Acute Liver Failure Induced by Viral HepatitisJournal of immunology researchJanuary 1, 2018Melgaço JG, Veloso CE, Pacheco-Moreira LF, Vitral CL, Pinto MA.at 5 μm, and stained with antibodies to membrane attack complex C5b/9 (clone: aE11, Santa Cruz cat #SC-58935, Brazil); the C3a component (clone: K13/16, Santa Cruz cat #SC-47688, Brazil) and C5a component (clone:

(10) Sublytic C5b-9 triggers glomerular mesangial cell apoptosis via XAF1 gene activation mediated by p300-dependent IRF-1 acetylationCell death & diseaseApril 17, 2014W Qiu, J Zhou, G Zhu, D Zhao, F He, J Zhang, Y Lu, T Yu, L Liu, Y Wangapoptosis. Materials and Methods Reagents and animals Monoclonal antibodies (Abs) against IRF-1 (sc-640), C5b-9 (sc-58935), His (sc-53073) and Thy-1 antigen (OX-7, sc-53116) as well as polyclonal Abs against PCAF (sc-8999)

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C5b-9 (aE11) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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C5b-9 (aE11) Antibody from Santa Cruz Biotechnology, Inc.

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